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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG2
All Species:
27.58
Human Site:
S176
Identified Species:
46.67
UniProt:
Q9UNQ0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNQ0
NP_004818.2
655
72314
S176
G
L
D
K
V
A
D
S
K
V
G
T
Q
F
I
Chimpanzee
Pan troglodytes
XP_526633
860
94544
S381
G
L
D
K
V
A
D
S
K
V
G
T
Q
F
I
Rhesus Macaque
Macaca mulatta
Q5MB13
654
72441
S176
G
L
D
K
V
A
D
S
K
V
G
T
Q
F
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMS5
657
72959
S175
G
L
E
K
V
A
D
S
K
V
G
T
Q
F
I
Rat
Rattus norvegicus
Q80W57
657
72942
S175
G
L
D
K
V
A
D
S
K
V
G
T
Q
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510302
654
72378
S173
G
L
T
K
V
A
D
S
K
V
G
T
Q
F
T
Chicken
Gallus gallus
XP_421638
651
72109
A178
G
L
S
K
V
A
D
A
K
V
G
T
E
L
I
Frog
Xenopus laevis
NP_001091141
661
73548
S174
G
L
T
K
V
A
D
S
K
V
G
T
Q
F
I
Zebra Danio
Brachydanio rerio
NP_001036240
643
71395
A169
E
L
G
L
S
K
V
A
D
S
R
V
G
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10090
687
75654
V212
H
L
T
Y
R
Q
R
V
A
R
V
D
Q
V
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11180
598
66888
Q133
T
V
I
G
I
P
N
Q
L
K
G
L
S
C
G
Sea Urchin
Strong. purpuratus
XP_789781
628
69714
R163
V
S
G
G
E
R
K
R
T
N
I
G
M
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93YS4
751
82913
S199
V
L
A
L
M
G
P
S
G
S
G
K
T
T
L
Baker's Yeast
Sacchar. cerevisiae
P25371
1049
117213
I521
I
I
D
I
K
D
R
I
I
G
N
E
F
D
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.4
96.6
N.A.
N.A.
81.8
81.4
N.A.
75.8
62.4
68.2
60.9
N.A.
31.5
N.A.
29.6
45
Protein Similarity:
100
75.9
97.7
N.A.
N.A.
89.6
89.1
N.A.
88.2
78.3
82.1
77.8
N.A.
51.6
N.A.
48.4
63.8
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
86.6
73.3
93.3
6.6
N.A.
20
N.A.
6.6
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
93.3
N.A.
86.6
86.6
93.3
13.3
N.A.
20
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
58
0
15
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
36
0
0
8
58
0
8
0
0
8
0
8
0
% D
% Glu:
8
0
8
0
8
0
0
0
0
0
0
8
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
50
0
% F
% Gly:
58
0
15
15
0
8
0
0
8
8
72
8
8
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
8
8
0
0
8
8
0
8
0
0
0
50
% I
% Lys:
0
0
0
58
8
8
8
0
58
8
0
8
0
0
0
% K
% Leu:
0
79
0
15
0
0
0
0
8
0
0
8
0
8
15
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
0
0
0
0
58
0
8
% Q
% Arg:
0
0
0
0
8
8
15
8
0
8
8
0
0
0
8
% R
% Ser:
0
8
8
0
8
0
0
58
0
15
0
0
8
0
0
% S
% Thr:
8
0
22
0
0
0
0
0
8
0
0
58
8
15
15
% T
% Val:
15
8
0
0
58
0
8
8
0
58
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _